Creating new approaches to develop Personalized Analgesics®
-
The clinical success rate for developing an analgesic is 2% - five times lower than other therapeutic areas.
-
Current treatment options are limited with only 1 in 8 people receiving satisfactory pain relief with standard of care.
-
We have to change how we conduct R&D and link research to specific pain conditions to create Personalized Analgesics®.
Keys to Analgesic Innovation
01
understand the patient
Listen and learn from patients to create patient inspired R&D
02
Disease understanding
Increase knowledge of the 100+ conditions associated with chronic pain
03
link target to disease
Move away from relying on 'preclinical' data to define clinical development
04
Develop in the right patients
Break away from only developing in the ~10 regulatory approved conditions
05
create the right patient outcomes
Develop patient outcome measures based on patients needs for each condition
06
increase female focused research
Take into account inherent gender bias and explore female pain conditions